The Laser Biomedical Research Center was established in October 1985 as a National Research Resource Center in laser biomedicine under support of the Biomedical Research Technology Program and since 2012 under support of the National Institute of Biomedical Imaging and Bioengineering, a Biomedical Technology Resource Center of the National Institutes of Health. The LBRC's mission is to develop the basic scientific understanding and new techniques required for advancing the clinical applications of lasers and spectroscopy.

Researchers use the LBRC's resources to exploit laser-based novel imaging and spectroscopy techniques for medical applications such as the spectral diagnosis of disease, and investigation of biophysical and biochemical properties of cells and tissues. A unique feature of the LBRC is its ability to form strong clinical collaborations with outside investigators in areas of common interest that further the Center's mandated research objectives.

As a NIBIB-Supported Biomedical Technology Resource Center, the LBRC makes available its facilities, along with technical and scientific support, to outside researchers for the purpose of pursuing independent research projects in the area of laser biomedical applications. The facilities are available on a time-shared basis, free-of-cost policy to qualified scientists, engineers and physicians throughout the United States. For additional information, please read the Guidelines for Use of LBRC Facilities.